The combined application of two insecticides with different modes of action (MoA) is an increasingly common approach to insect pest management. Insecticide mixtures (tank-mix or pre-formulated mixture) are applied to crops for pest management for many different reasons. These reasons include to broaden spectrum, to combine different technical characteristics of insecticides, or to combine two modes of action to control species where single compound applications do not provide sufficient control. Mixing insecticides, may also offer a benefit for insecticide resistance management (IRM). In the guidance document IRAC presents an up-dated mixture statement and the key considerations supporting it.